BCG-HO

Goal

The goal of our BCG-HO working group is the harmonization of cytogenomics testing in hematological malignancies and solid tumours among the Belgian genetic centers.

President :

Barbara Dewaele

Contact: Barbara.Dewaele@uzleuven.be

Secretary :

Mauricette Jamar & Catherine Menten

Contact: Mauricette.Jamar@chuliege.be

Member list :

• Antwerp University Hospital
  • Liesbeth Rooms
  • Sigri Beckers
• Ghent University Hospital
  • Nadine Van Roy
• IPG
  • Alice Hoche
  • Barbara Lambert
  • Christopher Rifaut
  • Cindy Dressen
  • Sébastien Toffoli
  • Tiberio Sticca
• Leuven University Hospital
  • Barbara Dewaele
  • Geneviève Ameye
  • Isabelle Vanden Bempt
  • Jolien De Bie
  • Justine Vanhevel
  • Katrina Rack
  • Lucienne Michaux
• Liège
  • Catherine Menten
  • Céline Lete
  • Mauricette Jamar
  • Sabine Franke
• UCL
  • Anne De Leener
  • Judith Luciani
  • Patrizia Chiarappa
  • Shaleena Horion
• ULB
  • Pierre Heimann

Recommendations/guidelines acquired cytogenomics:

• “European recommendations and quality assurance for cytogenomic analysis of haematological neoplasms (Rack et al 2019a) and Guidance for reporting the interpretation of cytogenomic test results in haematological neoplasms” (Rack et al 2019b)
• “Cytogenetics in the management of T-cell acute lymphoblastic leukemia (T-ALL): Guidelines from the Groupe Francophone de Cytogénétique Hématologique (GFCH)” (De Bie et al 2023)
• 2022 WHO classification of Haematolymphoid Tumours: Myeloid and Histiocytic/Dendritic Neoplasms
• 2022 WHO classification of Haemotolymphoid Tumours: Lymphoid Neoplasms
• 2022 ICC: D Arber, et al. International Consensus Classification of Myeloid Neoplasms and Acute Leukemias: integrating morphologic, clinical, and genomic data, Blood 2022;140(11):1200-1228.
• 2022 ICC: E. Campo, et al. The International Consensus Classification of Mature Lymphoid Neoplasms : a report from the Clinical Advisory Committee. Blood (2022) 140 (11): 1229–1253.
• ELN 2022: H. Döhner , et al. Diagnosis and management of AML in adults: 2022 recommendations from an international expert panel on behalf of the ELN. Blood (2022) 140 (12): 1345–1377.
• Guidelines Netherlands: verworven cytogenetica: VKGL: https://www.vkgl.nl/nl/kwaliteit/formulieren-documenten-kwaliteit/7-veldnormen
• Guidelines France: http://www.eaclf.org/docs/GBPcyto/GBPC-ACLF_15122021.pdf
  
  

Links to clinical trials in Belgium with great impact on acquired cytogenomics:

• ALLTogether1: A trial for children and young adults with acute lymphoblastic leukaemia (ALL)
  
  

Other interesting links:

• Limitative list Hemato-Onco 2023: https://www.college-genetics.be/nl/voor-de-professionele/good-practice-et-richtlijnen-voor-beroepsbeoefenaars/limitatieve-lijst.html
• ISCN 2020: https://iscn.karger.com/ or https://karger.com/cgr/article/161/5/223/819663/International-System-for-Human-Cytogenetic-or 
• Atlas Genetics and Cytogenetics
• RIZIV/INAMI article 33: https://www.riziv.fgov.be/nl/nomenclatuur/nomen/Paginas/nomen-artikel33.aspx or https://www.riziv.fgov.be/fr/nomenclature/nomenclature/Pages/nomen-article33.aspx
• RIZIV/INAMI article 33bis : https://www.riziv.fgov.be/nl/nomenclatuur/nomen/Paginas/nomen-artikel33bis.aspx or https://www.riziv.fgov.be/fr/nomenclature/nomenclature/Pages/nomen-article33bis.aspx
• RIZIV/INAMI article 33ter : https://www.riziv.fgov.be/nl/nomenclatuur/nomen/Paginas/nomen-artikel33ter.aspx or https://www.riziv.fgov.be/nl/nomenclatuur/nomen/Paginas/nomen-artikel33ter.aspx